Table 4.
Multivariable multinomial logistic regression analyses of baseline demographic characteristics, drug use behaviours, and social-structural exposures associated with different trajectory classes among 2057 people who use injection drugs, the Vancouver Injection Drug Users Study and AIDS Care Cohort to Evaluate Exposure to Survival Services, Vancouver, British Columbia, Canada, 1996-2017.
| Adjusted Odds Ratio (95% Confidence Interval) |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Characteristics | Persistent injection vs. Early cessation |
P | Persistent injection with late cessation vs. Early cessation |
P | Gradual cessation vs. Early cessation |
P | Early decrease with late relapse vs. Early cessation |
P | Persistent injection vs. Early decrease with late relapse |
P |
| Younger age, per year | 1.02 (1.00, 1.04) | 0.041 | 1.03 (1.01, 1.04) | 0.007 | 1.01 (1.00, 1.03) | 0.133 | 1.00 (0.98, 1.02) | 0.847 | 1.02 (1.00, 1.04) | 0.036 |
| Male | 0.86 (0.63, 1.18) | 0.358 | 1.28 (0.91, 1.81) | 0.162 | 1.19 (0.87, 1.62) | 0.278 | 1.10 (0.75, 1.61) | 0.635 | 0.79 (0.55, 1.11) | 0.172 |
| Not being in a stable relationship a | 1.64 (1.18, 2.27) | 0.003 | 1.59 (1.12, 2.27) | 0.010 | 1.44 (1.06, 1.97) | 0.020 | 1.12 (0.76, 1.64) | 0.566 | 1.46 (1.02, 2.09) | 0.038 |
| Daily heroin injection a | 1.41 (1.03, 1.93) | 0.030 | 1.01 (0.72, 1.42) | 0.949 | 1.36 (1.01, 1.83) | 0.046 | 1.01 (0.70, 1.47) | 0.956 | 1.40 (1.00, 1.95) | 0.051 |
| Binge injection drug use a | 1.63 (1.19, 2.22) | 0.002 | 1.26 (0.90, 1.77) | 0.183 | 1.77 (1.31, 2.40) | <0.001 | 1.23 (0.85, 1.78) | 0.277 | 1.32 (0.95, 1.84) | 0.096 |
| Year of enrollment | 1.03 (1.00, 1.06) | 0.061 | 1.08 (1.05, 1.12) | <0.001 | 1.06 (1.03, 1.09) | <0.001 | 0.95 (0.92, 0.99) | 0.006 | 1.08 (1.05, 1.12) | <0.001 |
| Adjusted Odds Ratio (95% Confidence Interval) |
||||||||||
| Characteristics | Persistent injection with late cessation vs. Early decrease with late relapse |
P | Gradual cessation vs. Early decrease with late relapse |
P | Persistent injection vs. Gradual cessation |
P | Persistent injection with late cessation vs. Gradual cessation |
P | Persistent injection vs. Persistent injection with late cessation |
P |
| Younger age, per year | 1.03 (1.01, 1.05) | 0.007 | 1.02 (1.00, 1.03) | 0.112 | 1.01 (0.99, 1.02) | 0.451 | 1.01 (1.00, 1.03) | 0.100 | 0.99 (0.98, 1.01) | 0.366 |
| Male | 1.17 (0.80, 1.70) | 0.421 | 1.08 (0.77, 1.52) | 0.653 | 0.73 (0.56, 0.94) | 0.015 | 1.08 (0.81, 1.44) | 0.608 | 0.67 (0.50, 0.91) | 0.010 |
| Not being in a stable relationship a | 1.42 (0.97, 2.09) | 0.071 | 1.29 (0.92, 1.82) | 0.146 | 1.13 (0.86, 1.49) | 0.375 | 1.10 (0.81, 1.49) | 0.528 | 1.03 (0.74, 1.42) | 0.871 |
| Daily heroin injection a | 1.00 (0.70, 1.44) | 0.998 | 1.34 (0.97, 1.86) | 0.075 | 1.04 (0.81, 1.33) | 0.761 | 0.75 (0.56, 0.98) | 0.037 | 1.40 (1.04, 1.87) | 0.025 |
| Binge injection drug use a | 1.02 (0.72, 1.46) | 0.895 | 1.44 (1.05, 1.99) | 0.025 | 0.92 (0.72, 1.17) | 0.480 | 0.71 (0.54, 0.93) | 0.014 | 1.29 (0.97, 1.72) | 0.081 |
| Year of enrollment | 1.14 (1.10, 1.18) | <0.001 | 1.12 (1.08, 1.15) | <0.001 | 0.97 (0.95, 0.99) | 0.004 | 1.02 (1.00, 1.05) | 0.064 | 0.95 (0.92, 0.97) | <0.001 |
a
Denotes behaviours and events in the previous six months, measured at baseline.