Table 1. Incidence of GATA-3 and CDX-2 positivity in breast, GI and lung cancer.
IHC | Breast cancer | GI malignancies | Lung |
---|---|---|---|
GATA-3 | 80–90% [9] |
<7% [9] | <10% [9] |
CDX -2 | Not seen | 100% – Colorectal >50% – gastric adenocarcinoma >33% – pancreatobiliary tract carcinomas. [10] |
40% – 50% of the non-mucinous adenocarcinomas (but along with TTF-1) [11] |
GI – Gastrointestinal;
TTF-1 – Thyroid transcription factor-1.