TABLE 2. Epidemiological data of five carbapenemase-producing mcr-1 positive Enterobacterales clinical isolates.

INEI ID	Species	Date	Sample	Hosp.	Province	Genes	CIM COL	Resistance profile	ST
M17386	E. coli	May 2014	Blood	A	CABA	blaNDM-1; blaCMY-6; mcr-1	≥ 4μg/mL	3GC, CBP, GEN, AMK, COL	10
M19637	E. coli	September 2015	Blood	B	Córdoba	blaKPC-2; mcr-1	≥ 4μg/mL	3GC, CBP, CIP, MIN, SXT, COL	156
M21069	E. coli	April 2016	Screening	C	Santa Cruz	blaKPC-2; mcr-1	≥ 4μg/mL	3GC, CBP, TET, MIN, COL	5208-like
M23101	E. coli	March 2018	Screening	D	CABA	blaNDM-1; blaCMY-6; mcr-1	≥ 4μg/mL	3GC, CBP, CIP, TET, MIN, GEN, AMK, SXT, NIT, COL	354
M23335	E. coli	May 2018	Urine	E	Entre Ríos	blaNDM-1; blaCMY-6; mcr-1	≥ 4μg/mL	3GC, CBP, CIP, GEN, AMK, COL	8492


Note: Hosp = hospital; CABA = Ciudad Autonoma de Buenos Aires; 3GC = third generation cephalosporins (cefotaxime and/or ceftazidime); CBP = carbapenem (ertapenem and/or imipenem); GEN = gentamicin; AKN = amikacin; COL = colistin; CIP = ciprofloxacin; MIN, minocycline; SXT = trimethoprim-sulfamethoxazole; TET = tetracycline; NIT = nitrofurantoin; NA = not applicable; ST = sequence type. ST5208-like is a SLV of ST5208 (adk: 10; fum: 7; gyr: 265; icd: 8; mdh: 12; purA: 8; recA: 194).


Source: Prepared by the authors from the study results.