. 2020 Aug 18;48(16):8901–8913. doi: 10.1093/nar/gkaa654

Table 2.

Predictions of nearest neighbor free energy parameters for guanosine·5-methylcytidine (G·m⁵C), N⁶-methyladenosine·uridine (m⁶A·U), and 2-aminopurineriboside·uridine (2AP·U) with average differences from comparable Watson–Crick parameters. X·Z base pairs represent the modified base pair in column headings, where X is first nucleotide listed (purine) and Z is the second (pyrimidine)

	m⁶A·U	G·m⁵C	2AP·U
AX	−0.91 ± 0.13	−1.86 ± 0.06	−1.03 ± 0.20
UZ	−0.91 ± 0.13	−1.86 ± 0.06	−1.03 ± 0.20
CX	−1.84 ± 0.47	−2.62 ± 0.17	−1.78 ± 0.28
GZ	−1.84 ± 0.47	−2.62 ± 0.17	−1.78 ± 0.28
GX	−1.94 ± 0.06	−2.89 ± 0.07	−1.99 ± 0.08
CZ	−1.94 ± 0.06	−2.89 ± 0.07	−1.99 ± 0.08
UX	−1.15 ± 0.09	−2.00 ± 0.28	−1.21 ± 0.22
AZ	−1.15 ± 0.09	−2.00 ± 0.28	−1.21 ± 0.22
XA	−0.90 ± 0.07	−2.06 ± 0.14	−0.98 ± 0.06
ZU	−0.90 ± 0.07	−2.06 ± 0.14	−0.98 ± 0.06
XC	−1.75 ± 0.03	−3.05 ± 0.86	−2.05 ± 0.25
ZG	−1.75 ± 0.03	−3.05 ± 0.86	−2.05 ± 0.25
XG	−1.84 ± 0.07	−3.02 ± 0.08	−1.92 ± 0.13
ZC	−1.84 ± 0.07	−3.02 ± 0.08	−1.92 ± 0.13
XU	−0.86 ± 0.18	−1.96 ± 0.13	−1.05 ± 0.18
ZA	−0.86 ± 0.18	−1.96 ± 0.13	−1.05 ± 0.18
ΔA-U	N/A	0.24	0.13
ΔG-C	0.20	N/A	N/A