Table 2.
Top five BioCarta pathways found to have higher pathway activity scores in the B cell cluster relative to other cells in the PBMC data set according to a Wilcoxon rank sum test. Pathways are ordered according to P-value from Wilcoxon test. The columns reflect the method used to compute the cell-specific pathway scores.
| VAM | GSVA | ssGSEA | z-scoring | PCA |
|---|---|---|---|---|
| IL5 | CTCF | CTCF | IL5 | BBCELL |
| BBCELL | BBCELL | ASBCELL | BBCELL | ASBCELL |
| ASBCELL | ASBCELL | BBCELL | BLYMPHOCYTE | TCRA |
| BLYMPHOCYTE | TH1TH2 | IL5 | MHC | CSK |
| INFLAM | IL5 | TH1TH2 | CTCF | TH1TH2 |