Prevalence, maximal/total occurrences and principal coordinates of PFAM core families. We inserted, for each core family (PFAM ID, first column), the percentage of proteomes in which it appears (prevalence, second column), the maximum number of times it occurs in one proteome (maximal occurrence, third column), the total number of times it is found among proteomes in the PFAM database (total occurrence, fourth column) and the percentage of variance explained by the firs two coordinates (PCo1 and PCo2, last two columns) when MDS is performed on sequences belonging to the five most abundant phyla (see Figure 3)