Table.
Patient characteristics before and after lockdown
| Before lockdown (n=686) | After lockdown (n=481) | p value | ||
|---|---|---|---|---|
| Age, years | ||||
| Mean | 65·8 (13·6) | 65·2 (12·7) | 0·49 | |
| Median | 66 (55–76) | 65 (55–75) | 0·44 | |
| <60 | 250 (36%) | 178 (37%) | 0·24* | |
| 60–79 | 305 (45%) | 229 (48%) | .. | |
| ≥80 | 131 (19%) | 74 (15%) | .. | |
| Sex | ||||
| Women | 177 (26%) | 124 (26%) | 0·99 | |
| Men | 509 (74%) | 357 (74%) | .. | |
| Regional prevalence of COVID-19 hospital admissions per 100 000 inhabitants | ||||
| >30 | 279 (41%) | 180 (37%) | 0·44† | |
| 15–29 | 267 (39%) | 204 (42%) | .. | |
| <15 | 140 (20%) | 97 (20%) | .. | |
| Hypertension | 350 (51%) | 247 (52%) | 0·84 | |
| Diabetes | 149 (22%) | 96 (20%) | 0·49 | |
| Obesity | 151 (22%) | 105 (23%) | 0·96 | |
| Smoking status | ||||
| No smoking | 292 (43%) | 215 (45%) | 0·50‡ | |
| Past smoking | 163 (24%) | 100 (21%) | .. | |
| Current smoking | 230 (34%) | 160 (34%) | .. | |
| STEMI | 331 (48%) | 252 (52%) | 0·16 | |
| Precise time from onset to admission not available | 17 (5%) | 24 (10%) | 0·049 | |
| Time from symptom onset to admission, min | 180 (108–390) | 180 (115–363) | 0·70 | |
| Primary percutaneous coronary intervention | 288 (87%) | 223 (89%) | 0·59 | |
| Fibrinolysis | 6 (2%) | 6 (3%) | 0·58 | |
| NSTEMI | 355 (52%) | 229 (48%) | 0·16 | |
| Coronary angiography within 24 h of admission | 224 (63%) | 143 (62%) | 0·87 | |
| Coronary angiography 24–72 h after admission | 102 (29%) | 57 (25%) | 0·31 | |
| Any percutaneous coronary intervention during hospital stay | 567 (83%) | 401 (85%) | 0·38 | |
| Maximal Killip class§ | ||||
| I | 543 (85%) | 344 (82%) | 0·61¶ | |
| II | 49 (8%) | 37 (9%) | .. | |
| III | 19 (3%) | 17 (4%) | .. | |
| IV | 29 (5%) | 22 (5%) | .. | |
| Duration of ICCU stay, days‖ | ||||
| Mean | 3·18 (2·9) | 3·37 (2·41) | 0·25 | |
| Median | 3 (2–4) | 3 (2–4) | 0·046 | |
| In-hospital death | 23 (3%) | 25 (5%) | 0·12 | |
Data are mean (SD), median (IQR), or n (%). ICCU=intensive cardiac care unit. NSTEMI=non-ST segment elevation myocardial infarction. STEMI=ST segment elevation myocardial infarction.
*
p value is for the comparison across all three age ranges.
†
p value is for the comparison across all three prevalence levels.
‡
p value is for the comparison across all three smoking statuses.
§
Not all patients had data available for maximal Killip class: before lockdown n=640; after lockdown n=420.
¶
p value is for the comparison across all four Killip classes.
‖
Not all patients had data available for duration of ICCU stay: before lockdown n=642; after lockdown n=440.