Table 1.

PredictSNP1 result of 13 non-synonymous mutations in YPEL3 gene.

Mutation	SNP ID	PredictSNP	Confidence score (%)	MAPP	Confidence score (%)	PhD-SNP	Confidence score (%)	PolyPhen-1	Confidence score (%)	PolyPhen-2	Confidence score (%)	SIFT	Confidence score (%)	SNAP	Confidence score (%)
V40M	rs759413482	Deleterious	64	–	–	Neutral	68	Deleterious	74	Deleterious	47	Deleterious	53	Deleterious	72
R57L	rs1378953136	Deleterious	65	Deleterious	48	Deleterious	86	Neutral	67	Deleterious	40	Deleterious	46	Deleterious	72
C61Y	rs753385457	Deleterious	87	Deleterious	77	Deleterious	89	Deleterious	74	Deleterious	65	Deleterious	53	Deleterious	87
D73N	rs568854299	Neutral	65	Neutral	66	Neutral	58	Neutral	67	Deleterious	47	Deleterious	45	Neutral	61
G98R	rs1234813494	Deleterious	87	Deleterious	88	Deleterious	77	Deleterious	74	Deleterious	65	Deleterious	79	Deleterious	81
G108S	rs760745635	Deleterious	87	Deleterious	57	Deleterious	88	Deleterious	74	Deleterious	81	Deleterious	79	Deleterious	56
D114N	rs936261369	Deleterious	87	Deleterious	77	Deleterious	86	Deleterious	59	Deleterious	81	Deleterious	53	Deleterious	72
E129Q	rs1316376447	Deleterious	61	Neutral	64	Deleterious	86	Deleterious	59	Deleterious	55	Deleterious	53	Neutral	55
A131T	rs1295542567	Deleterious	72	Deleterious	78	Deleterious	88	Neutral	67	Deleterious	81	Deleterious	45	Deleterious	62
A131V	rs373399618	Deleterious	87	Deleterious	77	Deleterious	88	Deleterious	59	Deleterious	81	Deleterious	53	Deleterious	72
I145T	rs757003466	Deleterious	87	Deleterious	78	Deleterious	73	Deleterious	74	Deleterious	65	Deleterious	79	Deleterious	62
G155A	rs752040143	Neutral	60	Deleterious	41	Neutral	51	Neutral	67	Deleterious	45	Deleterious	43	Neutral	50
D157N	rs767025068	Neutral	63	–	–	Neutral	68	Neutral	67	Deleterious	45	Deleterious	45	Neutral	55