Table 2.
Prediction of protein stability change due to nsSNPs in YPEL3 gene.
| Mutations | I-Mutant | MuPro | |||
|---|---|---|---|---|---|
| DDG value | RI | Stability | ΔΔG | Stability | |
| V40M | − 2.47 | 7 | Decrease | − 1.047 | Decreases |
| R57L | − 0.10 | 5 | Decrease | 0.363 | Increases |
| C61Y | 0.06 | 2 | Decrease | − 0.854 | Decreases |
| G98R | − 1.32 | 8 | Decrease | − 0.165 | Decreases |
| G108S | − 1.22 | 8 | Decrease | − 1.001 | Decreases |
| D114N | 0.84 | 2 | Decrease | − 0.954 | Decreases |
| E129G | − 1.52 | 7 | Decrease | − 1.174 | Decreases |
| A131T | − 0.54 | 5 | Decrease | − 0.950 | Decreases |
| A131V | − 0.40 | 1 | Decrease | − 0.391 | Decreases |
| I145T | − 0.61 | 3 | Decrease | − 2.272 | Decreases |