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. 2020 Sep 4;10:1650. doi: 10.3389/fonc.2020.01650

Table 1.

Features of included studies.

Study Year Country Study Case Age (Years) Cancer Stage Treatment Cut-off Determine the COX Survival Analysis SQ
Design Number Type (g/L) cut-off value
Yuk 2019 South Korea RTP, SC 610 - BCa Non-metastatic Surgery 1.1 ROC mul OS, CSS, PFS 8
Li 2019 China RTP, SC 885 67.0 ± 10.6 UTUC Non-metastatic Surgery 1.23 ROC mul OS, CSS, PFS 8
Ikeda 2019 Japan RTP, SC 243 61 (55–67) RCC Non-metastatic Surgery 1.42 Youden index mul CSS 8
Ha 2019 South Korea RTP, SC 118 69 (60–74) BCa Non-metastatic Surgery 1.3 ROC mul OS, CSS, PFS 7
Nishikawa 2018 Japan RTP, SC 135 69 (52–86) UTUC Non-metastatic Surgery 1.3 Reported mul PFS 7
Miyake 2018 Japan RTP, SC 74 - PCa Metastatic Chemotherapy 1.35 Median mul/uni OS, BRFS 6
Kang 2018 South Korea RTP, SC 158 58.6 ± 10.6 RCC Metastatic Targeted therapy 1.2 ROC mul OS, CSS 7
Canat 2018 Turkey RTP, SC 298 61.5 ± 13.2 RCC Non-metastatic Surgery 1.5 ROC uni CSS 6
Wang 2017 China RTP, SC 438 70 (65–74) PCa Non-metastatic Surgery 1.325 ROC uni/mul OS, BRFS 7
Lee 2017 South Korea RTP, MI 2965 55 (47–65) RCC Non-metastatic Surgery 1.5 ROC mul OS, CSS, PFS 7
Lee 2017 South Korea RTP, SC 623 65 (56–72) UTUC Non-metastatic Surgery 1.5 ROC mul OS, CSS, PFS 7
Ishihara 2017 Japan RTP, SC 118 - RCC Metastatic Surgery 1.24 ROC mul OS, CSS 6
Gorgel 2017 Turkey RTP, SC 153 61.7 ± 9.1 BCa Non-metastatic Surgery 1.3 ROC mul OS, CSS 6
Cho 2017 South Korea RTP, MI 1049 69 (61–74) UTUC Non-metastatic Surgery 1.6 ROC mul/uni OS, CSS, PFS 7
Bezan 2015 Austria RTP, SC 698 65 (56–73) RCC Non-metastatic Surgery 1.26 ROC mul OS, PFS 8

SQ, study quality according to the Newcastle-Ottawa scale; RTP, retrospective; SC, single center; MI, multi-institutional; UTUC, upper tract urothelial cancer; BCa, bladder cancer; PCa, prostate cancer; RCC, renal cell carcinoma; ROC, receiver-operating characteristic; OS, overall survival; CSS, cancer-specific cancer; PFS, progression-free survival; BRFS, biochemical recurrence-free survival.