Table 6.
The adjusted odds ratio (aOR) of adverse cardiometabolic outcomes in association with the android-to-gynoid-fat ratio (A/G) or total body fat percentage (TBF%) among children and adolescents with obesity in Hangzhou (China).
| Pre-pubertal boys* | Pubertal boys† | Pubertal girls‡ | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Prevalence | aOR (95% CI) | p | Prevalence | aOR (95% CI) | p | Prevalence | aOR (95% CI) | p | ||
| Impaired fasting glucose | A/G** | 20.9% | 0.89 (0.54, 1.46) | 0.64 | 18.2% | 1.12 (0.80, 1.57) | 0.50 | 32.1% | 1.20 (0.82, 1.76) | 0.36 |
| Total body fat % | 0.98 (0.83, 1.14) | 0.76 | 1.03 (0.95, 1.11) | 0.51 | 0.98 (0.88, 1.08) | 0.65 | ||||
| Impaired glucose tolerance | A/G** | 15.1% | 1.42 (0.79, 2.55) | 0.24 | 30.1% | 1.64 (1.07, 2.51) | 0.022 | 18.6% | 1.81 (1.10, 2.98) | 0.021 |
| Total body fat % | 1.07 (0.89, 1.29) | 0.49 | 1.03 (0.93, 1.14) | 0.60 | 0.96 (0.84, 1.10) | 0.57 | ||||
| Abnormal glycaemia | A/G ** | 35.3% | 1.06 (0.69, 1.62) | 0.78 | 39.8% | 1.51 (1.08, 2.11) | 0.016 | 40.7% | 1.42 (0.97, 2.09) | 0.07 |
| Total body fat% | 1.02 (0.89, 1.17) | 0.78 | 1.00 (0.93, 1.08) | 0.99 | 0.96 (0.87, 1.06) | 0.41 | ||||
| Hypertension | A/G** | 46.8% | 1.03 (0.69, 1.54) | 0.89 | 45.9% | 0.88 (0.63, 1.21) | 0.43 | 49.3% | 1.24 (0.87, 1.77) | 0.24 |
| Total body fat % | 1.01 (0.89, 1.15) | 0.83 | 1.02 (0.95, 1.10) | 0.53 | 0.99 (0.90, 1.08) | 0.83 | ||||
| Dyslipidaemia | A/G ** | 48.2% | 1.62 (1.05, 2.49) | 0.028 | 48.3% | 0.87 (0.64, 1.19) | 0.39 | 47.9% | 1.16 (0.81, 1.67) | 0.41 |
| Total body fat % | 0.94 (0.83, 1.07) | 0.37 | 0.96 (0.89, 1.03) | 0.29 | 0.95 (0.87, 1.05) | 0.30 | ||||
| Metabolic syndrome | A/G** | n/a | n/a | n/a | 45.5% | 0.97 (0.71, 1.31) | 0.83 | 44.3% | 1.31 (0.90, 1.90) | 0.15 |
| Total body fat% | n/a | n/a | n/a | 0.97 (0.90, 1.05) | 0.44 | 0.96 (0.88, 1.06) | 0.46 | |||
| NAFLD | A/G** | 61.2% | 2.57 (1.56, 4.21) | 0.0002 | 59.1% | 1.69 (1.18, 2.41) | 0.004 | 49.3% | 1.31 (0.88, 1.97) | 0.18 |
| Total body fat % | 1.14 (0.99, 1.31) | 0.07 | 1.15 (1.06, 1.26) | 0.001 | 1.02 (0.91, 1.12) | 0.78 | ||||
| Hyperuricaemia | A/G** | 8.6% | 1.22 (0.59, 2.54) | 0.59 | 24.4% | 1.43 (0.98, 2.10) | 0.06 | 12.1% | 1.72 (0.97, 3.03) | 0.06 |
| Total body fat% | 1.02 (0.81, 1.28) | 0.89 | 1.02 (0.94, 1.12) | 0.62 | 0.93 (0.80, 1.10) | 0.40 | ||||
The definitions of the adverse outcomes are provided in Table 1.
Statistically significant associations (p < 0.05) are shown in bold.
n/a, not applicable (current guidelines recommend that it is not appropriate to diagnose the metabolic syndrome in young children); CI, confidence interval; NAFLD, non-alcoholic fatty liver disease.
Models included the A/G and TBF% as independent variables.
Models included the A/G, TBF%, and testicular volume as independent variables; where the outcome was hypertension, models adjusted for height instead of testicular volume.
Models included the A/G, TBF%, and age as independent variables; where the outcome was hypertension, models adjusted for height instead of age.
aOR are shown in association with a change of 0.1 in the A/G.