Table 1.
Clinical scores at the time of enrollment (TP1), at the follow-up (TP2) and the difference in clinical scores between the two time-points (TP2-TP1) as a measure of clinical changes over time.
| TP1 | TP2 | TP2-TP1 | ||
|---|---|---|---|---|
| Disability and motor function | EDSS | 1.6 ± 0.3 | 1.7 ± 0.5 | — |
| 9-HPT (Arm function) | 19.8 ± 2.8 | 19.6 ± 2.7 | −0.21 ± 2.13 | |
| T25FWT (Leg function) | 4 ± 0.8 | 3.4 ± 0.5 | −0.62 ± 0.69 | |
| Cognition (BRB-N) | PASAT (cognitive) | 46.8 ± 10.4 | 48.7 ± 11.1 | 1.84 ± 6.71 |
| SRT-LTS (verbal memory) | 62.3 ± 7.2 | 65.7 ± 5 | 3.41 ± 6.32 | |
| SRT-CLTR (verbal memory) | 57.6 ± 11.4 | 61.6 ± 10 | 3.94 ± 9.15 | |
| SRT-D (verbal memory) | 11.4 ± 1.1 | 11.8 ± 0.5 | 0.38 ± 1.1 | |
| SDMT (attention) | 60.5 ± 17.3 | 57.2 ± 11.6 | −3.34 ± 18.7 | |
| SPART10/36 (visuospatial memory) | 23.2 ± 4.3 | 23.2 ± 3.9 | −0.03 ± 4.07 | |
| WLG (verbal fluency) | 27.6 ± 5.4 | 27.4 ± 7.9 | −0.19 ± 5.4 | |
| Mood and fatigue | HAD-A (anxiety) | 6 ± 4.1 | 5.7 ± 3.8 | −0.28 ± 3.34 |
| HAD- D (depression) | 2.9 ± 2.4 | 2.1 ±2.1 | −0.78 ± 2.56 | |
| FMSC-Cognitive | 23 ± 8.4 | 22.7 ± 9.6 | −0.31 ± 7.33 | |
| FMSC-Motor | 22.7 ± 9.6 | 23.1 ± 10.9 | −0.84 ±7.41 |
Values are expressed in mean ± standard deviation unless otherwise indicated.
BRB-N, Brief repeatable battery of neuropsychological tests; EDSS, Expanded Disability Status Scale; T25FW, Timed 25-Foot Walk—leg function; 9-HPT, 9 Hole Peg Tests -arm function; BRB-N, Brief Repeatable Battery of Neuropsychological Tests; PASAT, paced auditory serial addition test; SRT-LTS, selective reminding test-long term storage; SRT-CLTR, selective reminding test—Consistent long-term storage; SRT-D, selective reminding test-delayed; SDMT, symbol digit modalities test; cSPART 10/36, Spatial Recall Test; WLG: word list generation; HAD-A, Hospital Anxiety and Depression scale- Anxiety; HAD-D, Hospital Anxiety and Depression scale-Depression; FMSC, Fatigue scale for Motor and Cognitive functions.