Table 2.
Neural activation reflecting significant ROI-based results (p < 0.05 SVCFWE) for a regression of STAI-T on CS discrimination (CS+ > CS−) during fear acquisition training.
| STAI-T | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Contrast | Brain area | k | x | y | z | T | Z | p(uc) | p(SVCFWE) |
| CS+ > CS− | Putamen (R) | 230 | 28 | 12 | − 2 | 4.56 | 4.36 | < 0.001 | 0.001 |
| Putamen (L) | 75 | − 22 | 16 | − 4 | 4.06 | 3.91 | < 0.001 | 0.005 | |
| Amygdala (R) | 13 | 26 | − 10 | − 12 | 3.95 | 3.81 | < 0.001 | 0.003 | |
| Thalamus (L) | 32 | − 8 | − 8 | 8 | 3.60 | 3.50 | < 0.001 | 0.023 | |
| 10 | − 2 | − 20 | 12 | 3.50 | 3.40 | < 0.001 | 0.023 | ||
| Thalamus (R) | 12 | 4 | − 20 | 12 | 3.47 | 3.38 | < 0.001 | 0.033 | |
| CS− > CS+ | None | ||||||||
Cluster size k and coordinates x, y and z of the respective cluster are reported. Note that we used seven ROIs with the amygdala being the primary ROI and the other six being secondary ROIs. Correcting for multiple comparisons related to these seven regions would yield a corrected threshold of 0.007 (0.05/7), which the right and left thalamus would not meet for the full STAI-T. Coordinates are in MNI space.