Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 17;10:15316. doi: 10.1038/s41598-020-72136-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Effect of STAT3 decoy ODN transfection on upregulated HMGB1 levels in mice following CLP-induced sepsis. (A) HMGB1 protein levels in lung and liver tissues. Typical Western blots are shown in the top images in each panel. HMGB1 protein levels were normalized to GAPDH (n = 6). (B) HMGB1 mRNA in lung, liver, and kidney tissues. The mRNA levels of HMGB1 were quantified by real-time PCR and was normalized to GAPDH (n = 6). Tissues were harvested 18 h after surgery. (C) Serum HMGB1 levels in 18-h CLP mice (n = 6). *P < 0.05, **P < 0.01, and ***P < 0.001 compared with the respective control (18 h after sham operation). ^#P < 0.05 and ^##P < 0.01 compared with CLP alone.