Table 9.

Parameter threshold analysis to determine decision changing values for most uncertain parameters.

Value at which ICER is equal or exceeds threshold value
Description	Base case value	Light skin tone		Medium skin tone		Dark skin tone
		ICER = 404,074		ICER = £19,295		Intervention dominates
Lambda (£)		20,000	30,000	20,000	30,000	20,000	30,000
Rickets duration (yr.)	2	40.45	26.96	1.93	1.28	<0	<0
Intervention costs (excl. supplements, £/yr.)	10,000	<0	<0	13,526	63,877	275,731	399,832
Intervention OR for rickets incidence	0·410	<0.001	<0.001	0.427	0.597	0.822	0.866
Increase in woman supplementation rates (%)	17	<0	<0	20	54	>100	>100
Increase in children supplementation rates	20·0	<0	<0	21	33	79	>100

Results of the threshold analysis testing baseline QoL presented in Supplementary Appendix.