TABLE 1.
Comparison of demographic and clinical variables in patients with PFS < 3 and PFS ≥ 3 in the training set.
| Parameter | Total | PFS < 3 year (n = 45) | PFS ≥ 3 year (n = 118) | P-value |
| Age | 54.45 ± 11.68 | 57.87 ± 11.13 | 53.15 ± 11.67 | 0.021 |
| Sex | 0.404 | |||
| Male | 59 (36.2%) | 14 (31.1%) | 45 (38.1%) | |
| Female | 104 (63.8%) | 31 (68.9%) | 73 (61.9%) | |
| Hypertension | 0.649 | |||
| No | 134 (82.2%) | 36 (80.0%) | 99 (83.1%) | |
| Yes | 29 (17.8%) | 9 (20.0%) | 20 (16.9%) | |
| Diabetes mellitus | 0.566 | |||
| No | 155 (95.1%) | 44 (97.8%) | 111 (94.1%) | |
| Yes | 8 (4.9%) | 1 (2.2%) | 7 (5.9%) | |
| WBC count 10∧9/L | 6.57 ± 2.29 | 6.92 ± 2.39 | 6.44 ± 2.26 | 0.238 |
| NEU count 10∧9/L | 4.25 ± 2.16 | 4.99 ± 2.31 | 3.97 ± 2.03 | 0.007 |
| RBC count 10∧12/L | 4.53 ± 0.57 | 4.57 ± 0.49 | 4.52 ± 0.60 | 0.585 |
| MON count 10∧9/L | 0.40 ± 0.43 | 0.32 ± 0.26 | 0.43 ± 0.48 | 0.178 |
| LYM count 10∧9/L | 1.83 ± 0.55 | 1.64 ± 0.48 | 1.91 ± 0.56 | 0.004 |
| PLT count 10∧9/L | 239.77 ± 82.33 | 246.33 ± 70.55 | 237.28 ± 86.55 | 0.532 |
| HGB g/L | 133.75 ± 15.63 | 133.06 ± 14.42 | 134.01 ± 16.12 | 0.730 |
| FIB g/L | 2.99 ± 0.91 | 3.61 ± 1.16 | 2.73 ± 0.65 | < 0.001 |
| NLR | 2.55 ± 1.70 | 3.24 ± 1.39 | 2.29 ± 1.75 | 0.001 |
| Tumor size cm | 4.93 ± 1.44 | 5.55 ± 1.34 | 4.69 ± 1.41 | 0.001 |
| Tumor location | 0.082 | |||
| Non-skull base | 124 (76.1%) | 30 (66.7%) | 94 (79.7%) | |
| Skull base | 39 (23.9%) | 15 (33.3%) | 24 (20.3%) | |
| Extent of resection | 0.012 | |||
| Simpson Grade I-II | 141 (86.5%) | 34 (75.6%) | 107 (90.7%) | |
| Simpson Grade III-V | 22 (13.5%) | 11 (24.4%) | 11 (9.3%) | |
| Skull invasion | 0.321 | |||
| No | 97 (59.5%) | 24 (53.3%) | 73 (61.9%) | |
| Yes | 66 (40.5%) | 21 (46.7%) | 45 (38.1%) | |
| Peritumoral edema | 0.321 | |||
| Mild (≤1 cm) | 66 (40.5%) | 21 (46.7%) | 45 (38.1%) | |
| Severe (>1 cm) | 97 (59.5%) | 24 (53.3%) | 73 (61.9%) | |
| Brain invasion | 0.692 | |||
| No | 72 (44.2%) | 21 (46.7%) | 51 (43.2%) | |
| Yes | 91 (55.8%) | 24 (53.3%) | 67 (56.8%) | |
| Mitotic level | 0.132 | |||
| <4/HPF | 102 (62.6%) | 24 (53.3%) | 78 (66.1%) | |
| ≥4/HPF | 61 (37.4%) | 21 (46.7%) | 40 (33.9%) | |
| Ki-67 index | 0.563 | |||
| <5 | 100 (61.3%) | 26 (57.8%) | 74 (62.7%) | |
| ≥5 | 63 (38.7%) | 19 (42.2%) | 44 (37.3%) | |
| PORT | 0.095 | |||
| No | 136 (83.4%) | 34 (75.6%) | 102 (86.4%) | |
| Yes | 27 (16.6%) | 11 (24.4%) | 16 (13.6%) |
Values are reported as number, number(%), and mean ± standard deviation. PFS, progression-free survival; WBC, white blood cell; NEU, neutrophil; RBC, red blood cell; MON, monocyte; LYM, lymphocyte; PLT, platelet; HGB, hemoglobin; FIB, fibrinogen; NLR, neutrophil-lymphocyte ratio; PORT, postoperative radiation therapy.