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. 2020 Sep 4;11:1099. doi: 10.3389/fphys.2020.01099

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Copyright © 2020 Hooper, Jones, Smith, Williams and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Skipped exon usage during facial development. (A) Venn diagram showing the differentially used SE events called across age, layer, and prominence comparisons, but omitting the nasal epithelium (NE) samples. The numbers of shared or unique SE events are marked in the corresponding area. (B) Boxplots of the FDR of differentially used SE events across age, layer, and prominence. *Significant with t-test. (C) GO Biological Process (GO_BP) term enrichment for genes associated with differentially used SE events across layer, age, and prominence with adjusted p-value < 0.05. Note that manual curation was used so that only the most significant term is shown in the bar charts for similar terms. The full list of enriched terms is available in Supplementary Table 6.