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. 2020 Sep 15;5(5):e00724-20. doi: 10.1128/mSystems.00724-20

TABLE 3.

List of genes dysregulated in the PBMCs of dengue patients and associated pathways

Description −Log10(P) Hits
M5913: hallmark interferon gamma response 2.4 IRF4|PTGS2|NAMPT|USP18
M5922: hallmark unfolded protein response 3.3 SLC1A4|WFS1|XBP1|CHAC1
GO:0001568: blood vessel development 4 CAV1|COL1A1|COL1A2|EGR1|EPHB2|SMAD6|MCAM|PTGS2|XBP1
GO:0071560: cellular response to transforming
growth factor beta stimulus
4.2 CAV1|COL1A1|COL1A2|SMAD6|PMEPA1|CGN
M5890: hallmark TNFA signaling via NFKB 4.3 HBEGF|EGR1|MXD1|PTGS2|NAMPT|PMEPA1
GO:1903522: regulation of blood circulation 4.5 ADRA2B|ASPH|CAV1|HBEGF|JUP|PTGS2|THRB
GO:0097193: intrinsic apoptotic signaling pathway 4.5 BCL2L1|CAV1|E2F2|WFS1|XBP1|CUL3|CHAC1
M5945: hallmark heme metabolism 7.7 ANK1|E2F2|MXI1|SLC2A1|SLC6A9|TMCC2|FAM46C|RBM38|RANBP10