Table 1.
Comparison of demographic parameters, medical history, and clinical features in endometrial cancer group, benign group, and healthy group.
| Healthy (n = 43) | pa | Benign (n = 41) | pb | EC (n = 42) | |
|---|---|---|---|---|---|
| Median (min-max)/Mean ± SD | Median (min-max)/Mean ± SD | Median (min-max)/Mean ± SD | |||
| Age (years old) | 47.00 (40.00–59.00) | 0.002 | 46.00 (22.00–56.00) | <0.001 | 52.50 (31.00–70.00) |
| EpCAM (pg/ml) | 187.66 (111.68–280.47) | <0.001 | 199.16 (69.38–381.70) | 0.004 | 241.22 (133.39–380.97) |
| TGM2 (pg/ml) | 473.64 (0–6,300.00) | 0.429 | 369.80 (0–5,010.23) | <0.001 | 500.72 (213.72–6,040.93) |
| IL-33 (pg/ml) | 2.22 (0–68.80) | 0.004 | 7.02 (83–84.00) | 0.466 | 4.65 (0.30–69.91) |
| CA125 (ng/ml) | 12.08 (5.36–50.96) | <0.001 | 15.06(6.37-81.94) | 0.004 | 20.73 (6.84–147.70) |
| HE4 (pmol/ml) | 32.51 (21.21–48.88) | <0.001 | 46.26 (32.09–75.54) | 0.001 | 58.54 (30.98–455.40) |
| TG (mmol/L) | 1.16 (0.60–1.92) | 0.001 | 1.12 (0.64–16.00) | 0.007 | 1.51 (0.55–4.11) |
| TC (mmol/L) | 5.02 (3.41–6.03) | 0.961 | 4.81 (2.89–7.14) | 0.125 | 4.74 (2.49–7.80) |
| GLU (mmol/L) | 5.83 (5.09–6.67) | 0.993 | 5.42 (4.02–10.73) | 0.055 | 5.80 (4.09–14.40) |
| HDL (mmol/L) | 1.43 ± 0.33 | 0.032 | 1.22 ± 0.36 | 0.425 | 1.27 ± 0.30 |
| LDL (mmol/L) | 2.87 ± 0.59 | 0.334 | 2.47 ± 0.85 | 0.170 | 2.70 ± 0.87 |
The statistical analysis of EpCAM, TGM2, IL-33, CA125, HE4, TG, TC, and GLU are tested by Kruskal-Wallis. The statistical analysis of HDL and LDL are tested by LSD-t. p < 0.05 is considered as statistically significant. pa, Healthy vs. EC; pb, Benign vs. EC.