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Effect of β-hydroxybutyrate (BHB) on heteromeric Kv7.2 + Kv7.3, Kv7.2 + Kv7.3 + Kv7.3 M240R channels. (A) Current responses from the indicated heteromeric channels to voltage ramps from −80 to +20 mV. (B,C) Quantification of the effects of 100 μM BHB on the indicated heteromeric channels. Data are expressed as current density calculated at −40 mV (B) and in the V1/2 values. Current scale, 200 pA; time scale, 200 ms. * indicates p < 0.05 vs. corresponding controls.
