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. 2020 Sep 4;8:773. doi: 10.3389/fbioe.2020.00773

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Copyright © 2020 Balion, Sipailaite, Stasyte, Vailionyte, Mazetyte-Godiene, Seskeviciute, Bernotiene, Phopase and Jekabsone.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic activity of HROG36, C6, and A375 cells on PEG-CLP, PEG-CLP-RGD, and PEG-CLP-IKVAV hydrogels after 24 h (A) and 48 h (B). The metabolic activity of the cells corresponding to the proliferation intensity was assessed by Presto Blue^TM assay in three independent experimental sets, each of three replicates. RFU, relative fluorescence units. *Indicates a statistically significant difference compared with the samples of the same cell type grown on CLP-only containing hydrogels, ^∧-with samples on PEG-CLP-RGD hydrogels, ANOVA with post hoc LSD test, p < 0.05.