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. 2020 Sep 7;12:313–323. doi: 10.2147/JEP.S262026

Table 4.

Packed Cell Volume, Rectal Temperature, and Body Weight of Infected Mice Treated with Solvent Fractions of the Leaves Hypoestes forskalei in the 4-Day Suppressive Test

Groups Packed Cell Volume Rectal Temperature Body Weight
D0 D4 % Change D0 D4 % Change D0 D4 % Change
2% TW80 59.34±0.14 54.07±0.44 −8.88 36.52±0.14 34.64±0.35 −5.14 28.382±0.21 27.072±0.19 −4.61
CQ25 mg/kg 60.15±0.31 59.86±0.23 −0.48a3 35.48±0.04 35.49±0.15 0.03a3 28.082±0.44 28.422±0.22 1.21a3
200 mg/kg CF 59.53±0.13 55.94±0.53 −6.03a3b3 36.31±0.11 34.99±0.22 −3.64a3b3 28.142±0.09 26.962±0.33 −4.19a1b3
400 mg/kg CF 60.01±0.33 56.82±0.44 −5.31a3b3 36.20±0.08 35.34±0.65 −2.37a2b3 27.972±0.55 26.982±0.45 −3.54a1b3
600 mg/kg CF 60.71±0.23 57.82±0.37 −4.76a3b3 35.73±0.34 35.00±0.78 −2.04a2b3 28.162±0.33 27.212±0.39 −3.37a2b3
2% TW80 59.34±0.11 54.04±0.31 −8.93 36.52±0.14 34.59±0.71 −5.28 28.402±0.19 27.072±0.22 −4.68
CQ25 mg/kg 60.15±0.09 59.86±0.18 −0.48a3 35.49±0.43 35.49±0.65 0.00a3 28.102±0.36 28.422±0.21 1.14a3
200 mg/kg BF 59.46±0.23 56.3±0.22 −5.31a3b3d1e2 36.36±0.35 35.06±0.09 −3.57a1b3e2 28.012±0.39 26.852±0.19 −4.14a1b3
400 mg/kg BF 60.06±0.53 57.56±0.51 −4.16a3b3 36.25±0.22 35.43±0.55 −2.26a3b3 27.972±0.32 27.022±0.18 −3.40a1b3
600 mg/kg BF 60.76±0.33 58.52±0.27 −3.69a3b3 35.78±0.33 35.11±0.39 −1.87a3b3 27.662±0.52 26.802±0.23 −3.11a2b3
2% TW80 59.27±0.43 54.05±0.63 −8.70 36.5±0.24 34.59±0.44 −5.23 28.402±0.29 27.072±0.33 −4.68
CQ25 mg/kg 60.13±0.36 59.86±0.23 −0.45a3 35.49±0.55 35.48±0.67 −0.03a3 28.102±0.18 28.422±0.22 1.14a3
200 mg/kg AF 59.58±0.55 55.01±0.17 −7.67a3b3 36.38±0.08 34.95±0.77 −3.93a1b3 28.172±0.35 26.972±0.29 −4.26b3
400 mg/kg AF 60.05±0.73 55.7±0.39 −7.24a3b3 36.24±0.55 35.04±0.23 −3.31a2b3 28.012±0.36 26.822±0.24 −4.25 b3
600 mg/kg AF 60.69±0.43 56.52±0.53 −6.87a3b3 35.83±0.78 34.91±0.19 −2.57a2b3 28.232±0.56 27.122±0.22 −3.93 b3

Notes: Data are expressed as mean±SEM; n=6; CF, chloroform fraction; BF, butanol fraction; AF, aqueous fraction; a, compared to negative control; b, to CQ25 mg/kg; e, to 600 mg/kg; 1, P<0.05; 2, P<0.01; 3, P<0.001; 2% TW80, 2% Tween80; CQ, chloroquine; D0, pre -treatment value on day 0; D4, post-treatment value on day 4.