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. 2020 Sep 7;12:313–323. doi: 10.2147/JEP.S262026

Table 6.

Packed Cell Volume, Rectal Temperature, and Body Weight of Infected Mice Treated with n-Butanol Fraction of the Leaves of Hypoestes forskalei in Rane’s Test

Groups Packed Cell volume Rectal Temperature Body Weight
D3 D7 % Change D3 D7 % Change D3 D7 % Change
2% TW80 51.66±0.36 43.00±0.33 −16.76 35.23±0.24 33.38±0.25 −5.25 28.29±0.45 25.56±0.52 −9.65
CQ25 mg/kg 50.11±0.32 51.64±0.25 3.05a3 35.05±0.21 35.34±0.20 0.83a3 28.49±0.52 28.93±0.43 1.54a3
200 mg/kg 51.73±0.22 46.42±0.18 −10.26a3b3d2e3 35.18±0.15 33.70±0.18 −4.20a3b3d1e3 26.86±0.33 24.57±0.25 −8.52b3
400 mg/kg 51.64±0.25 47.66±0.22 −7.70a3b3 35.23±0.35 33.92±0.31 −3.72a3b3 28.08±0.43 25.9±0.42 −7.76a2b3
600 mg/kg 51.58±0.06 48.06±0.17 −6.82a3b3 35.23±0.19 34.1±0.21 −3.20a3b3 27.49±0.53 25.45±0.32 −7.42a2b3

Notes: Data are expressed as mean±SEM; n=6; a, compared to negative control; b, to CQ25 mg/kg; d, to 400 mg/kg; e, to 600 mg/kg; 1, P<0.05; 2, P<0.01; 3, P<0.001; 2% TW80, 2% Tween80; CQ, chloroquine; D3, pre-treatment value on day 3; D7, post- treatment value on day 7.