Table 6.
Packed Cell Volume, Rectal Temperature, and Body Weight of Infected Mice Treated with n-Butanol Fraction of the Leaves of Hypoestes forskalei in Rane’s Test
| Groups | Packed Cell volume | Rectal Temperature | Body Weight | ||||||
|---|---|---|---|---|---|---|---|---|---|
| D3 | D7 | % Change | D3 | D7 | % Change | D3 | D7 | % Change | |
| 2% TW80 | 51.66±0.36 | 43.00±0.33 | −16.76 | 35.23±0.24 | 33.38±0.25 | −5.25 | 28.29±0.45 | 25.56±0.52 | −9.65 |
| CQ25 mg/kg | 50.11±0.32 | 51.64±0.25 | 3.05a3 | 35.05±0.21 | 35.34±0.20 | 0.83a3 | 28.49±0.52 | 28.93±0.43 | 1.54a3 |
| 200 mg/kg | 51.73±0.22 | 46.42±0.18 | −10.26a3b3d2e3 | 35.18±0.15 | 33.70±0.18 | −4.20a3b3d1e3 | 26.86±0.33 | 24.57±0.25 | −8.52b3 |
| 400 mg/kg | 51.64±0.25 | 47.66±0.22 | −7.70a3b3 | 35.23±0.35 | 33.92±0.31 | −3.72a3b3 | 28.08±0.43 | 25.9±0.42 | −7.76a2b3 |
| 600 mg/kg | 51.58±0.06 | 48.06±0.17 | −6.82a3b3 | 35.23±0.19 | 34.1±0.21 | −3.20a3b3 | 27.49±0.53 | 25.45±0.32 | −7.42a2b3 |
Notes: Data are expressed as mean±SEM; n=6; a, compared to negative control; b, to CQ25 mg/kg; d, to 400 mg/kg; e, to 600 mg/kg; 1, P<0.05; 2, P<0.01; 3, P<0.001; 2% TW80, 2% Tween80; CQ, chloroquine; D3, pre-treatment value on day 3; D7, post- treatment value on day 7.