Table 5.
Association of donor-recipient genetics with graft loss. The low score group consisted of donor-recipient pairs carrying 0 or 1 variants in each considered locus, whilst the high score group are pairs with 2–4 variants. Ref., reference; OR, odds ratio; CI, 95% confidence interval. The covariates utilized to adjust the model are the same as those described in Table 3.
|
No graft loss |
Graft loss |
||||||
|---|---|---|---|---|---|---|---|
| Score | N | % | N | % | OR (CI) | p-value | |
| LEPR rs1805094 | Low | 206 | 84.4% | 55 | 87.3% | Ref. | |
| High | 38 | 15.6% | 8 | 12.7% | 0.58 (0.19–1.80) | 0.422 | |
| LEPR rs1137100 | Low | 177 | 72.8% | 48 | 80.0% | Ref. | |
| High | 66 | 27.2% | 12 | 20.0% | 0.71 (0.22–1.73) | 0.383 | |
| LEPR rs1137101 | Low | 98 | 40.2% | 32 | 53.3% | Ref. | |
| High | 146 | 59.8% | 28 | 46.7% | 0.45 (0.11–0.81) | 0.009 | |
| ADIPOQ rs1501299 | Low | 169 | 69.3% | 37 | 59.7% | Ref. | |
| High | 75 | 30.7% | 25 | 40.3% | 1.75 (0.68–3.44) | 0.198 | |
| ADIPOQ rs2241766 | Low | 204 | 84.6% | 48 | 82.8% | Ref. | |
| High | 37 | 15.4% | 10 | 17.2% | 1.26 (0.60–3.02) | 0.735 | |