Table 2.2.

the main laboratory tests and the positive rate of them in severe hepatitis patients with blood coagulopathy

Name	Changes	Normal reference value	Positive rate when severe hepatitis occurring (%)
1. Tests about clotting factors
PT	Lengthen	11–13 s	63–71
APTT	>10s	(37 ± 3.3)s	82–85
INR	–	1.0 ± 0.1	>80
HPT	Decrease	90.1% ± 13.4%	93
Fz	Decrease	2–4 g/L	16–20
Fγ:C	Increase	(103 ± 26)IU/L	100
TT	>3 s	16–18 s	–
2. Tests about anti-clotting factors
AT-β:A	Decrease	108.5 ± 5.3%	100
PC:A	Decrease	64–147%	84
3. Tests about fibrinolysis
tPA	Increase	(0.3–0.6) IU/mL	92
PAI	Decrease	(0.1 ± 1.0)Au/mL	76
PLG:Ag	Decrease	(0.22 ± 0.03)g/L	56
PL;A	Fibrinolysis: increase Hypercoagulability: Decrease	85.5% ± 27.83%	–
a2-PI	Decrease	0.8–1.2 inhibitory units/mL	55
3P test	–	Negative	negative
ELT	Shorten (<70 min)	Calcium addition method (129.8 ± 41.1)min Enzymolysis method (157.5 ± 59.1)min	–
FDPs	Decrease	urine<10 mg/L	85–90
D-Dimer	Increase	Negative (latex agglutination test) 0–0.256 mg/L (ELISA)	9–15
4. Test about platelets quality and quantity
PLT	Decrease	(100–300) × 109/L	–
PAR	Decrease	MAR (maximum aggregation rate) ADP (1.0 mmol/L)62.7% ± 16.1% ADP (0.5 mmol/L)37.4% ± 14.3% Adrenaline (0.4 mg/L)67.85% ± 17.8%	–
PF3aT	Decrease	The recalcification time of group is under 5 s longer than that of group	–
CRT (whole blood method)	–	Clot retraction rate 65.8% ± 11.0%; Clot retracts partly after 2 h, and retracts completely after 18–24 h	–