. 2020 Aug 13;119(6):1178–1192. doi: 10.1016/j.bpj.2020.08.001

Table 2.

Main and Total Effects of the IP₃R Gating Parameters on Ca²⁺ Transient Amplitude, Duration, Diastolic Ca²⁺, and Duty Cycle

Main Effect Coefficients	[IP₃]	t_max	K_c	K_h	K_t	k_f
Amplitude	027^a	0.00	0.03	0.19^a	0.00	0.03
Duration (FDHM)	0.17^a	0.00	0.01	0.12^a	0.00	0.50^a
Diastolic Ca²⁺	0.44^a	0.00	0.09	0.03	0.00	0.04
Duty cycle	0.23^a	0.00	0.01	0.16^a	0.00	0.33^a

Total Effect Coefficients	[IP₃]	t_max	K_c	K_h	K_t	k_f

Amplitude	0.63^a	0.04	0.43^a	0.46^a	0.02	0.13^a
Duration (FDHM)	0.33^a	0.00	0.19^a	0.19^a	0.00	0.54^a
Diastolic Ca²⁺	0.79^a	0.00	0.45^a	0.06	0.00	0.18^a
Duty cycle	0.45^a	0.00	0.25^a	0.24^a	0.00	0.38^a

Duration measured in FDHM.

Significant values.