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Western blotting analysis.Fig. 4 shows that the G. lucidum down-regulated the expression of JAK-1 and elevated the expression of Jak-1 in PC-3 cells. The G. lucidum significantly diminished the expression of STAT-3 protein and holds back the translocation of STAT-3 in PC-3 cells. The G. lucidum suppresses the cyclin-D1 expression and up lifted the Bax expression and declined the Bcl-2 expression in the PC-3 cells. β-actin was used as a internal control.
