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. 2020 Aug 19;9(9):515–522. doi: 10.1002/psp4.12538

Table 3.

Summary statistics of simulated steady‐state trough CSF concentrations (µg/mL) for proposed phase II doses

Dose, mg Simulated steady‐state trough CSF concentrations, μg/mL
Median, q50 q5 q95
250 0.076 0.029 0.191
1,250 0.369 0.128 0.936
3,500 1.07 0.403 2.79

CSF, cerebrospinal fluid; q, percentile.