Table 1.
Demographic, clinical, and laboratory characteristics of the KFD patients recruited in the study.
| Variable | Mean (SD) | N (%) | H/O KFDV Vaccination | ||
|---|---|---|---|---|---|
| No (n = 22) | Yes (n = 22) | P value | |||
| Mean age in year | 40.93 (13.1) | ||||
| Gender | |||||
| Male | 18 (40.9) | 11 | 7 | 0.3454 | |
| Female | 26 (59.1) | 11 | 15 | 0.4328 | |
| Hospitals | |||||
| CHC Valpoi, Goa | 23 (52.3) | 15 | 8 | 0.1444 | |
| JCH Thirthahalli, Karnataka | 13 (29.5) | 2 | 11 | 0.0125 | |
| RH Dodamarg, SDH Sawanthwad, PHC Banda Maharashtra | 8 (18.2) | 5 | 3 | 0.4795 | |
| Socio economic status# | |||||
| Low < 40 | 27 (61.3) | 14 | 13 | 0.8474 | |
| Middle 40–70 | 17 (38.7) | 8 | 9 | 0.8084 | |
| Clinical status (n = 44) | |||||
| Fever | 44 (100) | 22 | 22 | 1.0 | |
| Myalgia | 39 (88.6) | 18 | 22 | 0.108 | |
| General weakness | 37 (84.1) | 19 | 19 | 1.0 | |
| Headache | 37 (84.1) | 20 | 18 | 0.664 | |
| Nausea | 26 (59.1) | 12 | 15 | 0.537 | |
| Cough | 20 (45.5) | 9 | 12 | 0.547 | |
| Vomiting | 14 (31.2) | 10 | 5 | 0.203 | |
| Diarrhoea | 12 (27.3) | 7 | 5 | 0.736 | |
| Altered sensorium and/or seizure | 3 (6.8) | 3 | 0 | 0.233 | |
| Hemorrhagic signs | 1 (2.3) | 1 | 0 | 1.0 | |
| Hypotension | 18 (40.9) | 9 | 11 | 0.763 | |
| Deceased | 2 (4.5) | 2 | 0 | 0.488 | |
| Laboratory features | |||||
| Mean total leukocyte count/mm3 (n = 41) | 2,588 (1627) | 2,339 | 2,825 | 0.345 | |
| Mean platelet count × 103/µl (n = 39) | 124 (50) | 104 | 139 | 0.031* | |
| Aspartate aminotransferase IU/L (n = 25) | 208.7 (338) | 326 | 80 | 0.681 | |
| Alanine aminotransferase IU/L (n = 25) | 102.6 (136) | 147 | 54.6 | 0.907 | |
| Alkaline phosphatase IU/L (n = 23) | 211 (92.9) | 222.3 | 196.8 | 0.525 | |
| C-Reactive protein < 10 mg/dl (N = 24) | 2.6 (2.2) | 2.49 | 2.8 | 0.733 | |
| Mean duration hospitalization (days) (n = 43) | 5.2 (2.7) | 5.04 | 5.4 | 0.653 | |
| H/O of KFD vaccination | |||||
| Unvaccinated | 22 (50) | ||||
| Vaccinated at least one dose | 22 (50) | ||||
| Vaccinated two/three dose | 16 (36.4) | ||||
*Significant difference, #modified Udai Pareekh scale.