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. 2020 Sep 17;10:15296. doi: 10.1038/s41598-020-72338-3

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Monthly plasma cholesterol, LDL and HDL level and fasted triglyceride level vs diets in ApoE KO and Sprague Dawley rats. Cholesterol and LDL levels were significantly higher before the start of diet in ApoE KO rats compared to the Sprague Dawleys rats, (**) P < 0.0001; After 5 months of diet, cholesterol, LDL and triglyceride levels were significantly higher in ApoE KO rats fed on western diet compared to the ApoE KO and Sprague Dawley rats on standard diet, (**) P < 0.0001; HDL level was significantly higher in Sprague Dawley rats before and after control diet compared to the ApoE KO rats, (**) P < 0.0001; ANOVA, n = 8, n = 7.