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. 2020 Sep 17;10:15229. doi: 10.1038/s41598-020-71878-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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PSOn increases the antioxidant- and lipid metabolism-related gene expression. Determination of transcripts was made by total RNA extraction from liver tissue and quantitated by qPCR. Representative data are shown. The bars represent the mean ± SEM of the relative expression for each gene and the indicated mouse groups (Aox1, aldehyde oxidase; Gsta4, glutathione S-transferase 4; Nqo1, NADPH-quinone dehydrogenase 1; Nfe2, nuclear factor erythroid 2; Prdx1, peroxiredoxin 1). *p < 0.05; **p < 0.001 vs. HFD group.