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. 2020 Sep 17;11(9):766. doi: 10.1038/s41419-020-02938-4

Fig. 3. Anlotinib leads to apoptosis via endoplasmic reticulum stress.

Fig. 3

a Immunofluorescent analysis was performed to detect the ER luminal marker protein disulphide isomerase (PDI). b The expression of the indicated markers reflecting endoplasmic reticulum stress in three PC cell lines was examined by western blotting. cf PC cell apoptosis was detected using PI and Annexin-V-FITC staining. The data are presented as the mean ± SD from three independent experiments (***p < 0.001).