Table 2. Virus Titers and Log Reduction Value (LRV) of SARS-CoV-2 When Incubated With Various Concentrations of Povidone Iodine (PVP-I) and Controls for 30 Seconds.
| Test product | PVP-I concentration after 1:1 dilution, % | Virus titera | LRVb |
|---|---|---|---|
| PVP-I nasal antiseptic | |||
| 5.0% | 2.5 | <0.67 | 3.33 |
| 2.5% | 1.25 | <0.67 | 3.33 |
| 1.0% | 0.50 | <0.67 | 3.33 |
| Ethanol 70% | NA | <0.67 | 3.33 |
| Virus control | NA | 4.0 | NA |
Abbreviations: CCID50, 50% cell culture infectious dose; NA, not applicable; SARS-CoV-2, severe acute respiratory syndrome-coronavirus 2.
a
Log10 CCID50 of virus per 0.1 mL. The assay lower limit of detection is 0.67 log10 CCID50/0.1 mL.
b
Log reduction value is the reduction of virus compared with the virus control.