Table 2.
Differentially expressed cancer pathways between primary and metastatic samples (FDR < 0.05).
| Gain/Loss after metastasis | Differentially expressed pathways | FDR |
|---|---|---|
| Relative gain | cAMP signaling pathway | 6.88e-03 |
| Relative gain | ErbB signaling pathway | 2.09e-02 |
| Relative gain | Calcium signaling pathway | 4.39e-02 |
| Relative loss | Cytokine-cytokine receptor interaction | 4.37e-06 |
| Relative loss | Apoptosis | 8.53e-04 |
| Relative loss | JAK-STAT signaling pathway | 8.53e-04 |
| Relative loss | Wnt signaling pathway | 3.97e-03 |
| Relative loss | Hedgehog signaling pathway | 4.50e-03 |
| Relative loss | PI3K-Akt signaling pathway | 1.35e-02 |
| Relative loss | TGF-beta signaling pathway | 4.56e-02 |
| Relative loss | Notch signaling pathway | 4.56e-02 |