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. 2020 Sep 17;11(9):765. doi: 10.1038/s41419-020-02916-w

Fig. 4. CUDC-907 treatment inhibits lung cancer cell lines induced migration with or without TGFβ1 stimulation.

Fig. 4

a Migration assays performed with TGFβ1 stimulated CAF1 treated with 10 nM and 30 nM CUDC-907 and cocultured with lung cancer cell. After incubation for 24 h, cells that migrated through transwell membrane were fixed, stained and acquired. Scale bars: 25 µm. b Representative micrographs and graphic representation of the quantification of three independent experiments each using five random fields. c Western blot analysis of vimentin and vinculin. Error bars are ±SD. *, **, *** represent 907 treatment groups compared with DMSO group, respectively. *P < 0.05; **P < 0.01; ***P < 0.001. #, ##, ### represent T + 907 treatment groups compared with TGFβ1 group, respectively. #P < 0.05; ##P < 0.01; ###P < 0.001.