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EGCG inhibits 3CL-protease in vitro. (a) Indicated concentrations of EGCG were incubated with 3CL-protease, and the 3CL-protease activity was determined. The 3CL-protease activity was performed in triplicate, and the mean and standard deviation are shown. (b) IC50 of EGCG was calculated and shown in the graph. Control vs EGCG treatment: ∗p < 0.05,∗∗p < 0.01,∗∗∗p < 0.001.
