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. 2020 Sep 17;10:15263. doi: 10.1038/s41598-020-72261-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Gene Ontology analysis reveal compartment-specific enrichment of GO pathways in AF and NP cells. (a) Advanced bubble plot depicting molecular function-related pathways enriched in AF cells. (b) Advanced bubble plot showing molecular function-related pathways enriched in NP cells. Y-axis Labels represent pathway names while and enrichment score is shown on X-axis. The size and color of the bubble represent the number of genes enriched in each pathway and their enrichment significance. The bubble plots were generated using GraphPad Prism version 8.2.0. (c) Metabolic pathway analysis of glycolysis, TCA cycle, electron transport chain and pyruvate metabolism pathways in AF. (d) Metabolic Pathway analysis of glycolysis, TCA cycle, electron transport chain and pyruvate metabolism pathways in NP cells. Heatmap shows log10 transformed fold change in gene expression and were generated using GraphPad Prism version 8.2.0.