Figure 5.

Crocetin inhibited inflammatory response in irradiated IEC-6 cells. The levels of (a) TNF-α, (b) IL-1β, (c) IFN-γ, and (d) MPO in cell culture supernatants were measured on days 1, 3, 5, and 7 after radiation. Data were expressed as mean ± SD of three independent experiments. ∗P < 0.05 compared to the control group, ∗∗P < 0.05 compared to the IR group. TNF-α: tumor necrosis factor-α, IL-1β: interleukin-1β, IFN-γ: interferon-γ; MPO: myeloperoxidase; IR group: irradiation group, IEC-6 cells exposed to 10 Gy of radiation. Control group: IEC-6 cells without irradiation or crocetin.