Table 2.
Biological process of Compound-Xueshuantong Capsule in diabetic retinopathy treatment.
| ID | Description | Gene ID | Count |
|---|---|---|---|
| GO: 0004879 | Nuclear receptor activity | PGR/ESR1/AR/PPARG/NR3C1/RXRB/AHR | 7 |
| GO: 0098531 | Transcription factor activity, direct ligand regulated sequence-specific DNA binding | PGR/ESR1/AR/PPARG/NR3C1/RXRB/AHR | 7 |
| GO: 0003707 | Steroid hormone receptor activity | PGR/NR3C2/ESR1/AR/PPARG/NR3C1/RXRB | 7 |
| GO: 0001228 | Transcription activator activity, RNA polymerase II-specific | PGR/ESR1/AR/RELA/NR3C1/FOS/RXRB/HIF1A/NFE2L2/PARP1/IRF1 | 11 |
| GO: 0097153 | Cysteine-type endopeptidase activity involved in apoptotic process | CASP9/CASP3/CASP7/CASP1 | 4 |
| GO: 0005496 | Steroid binding | PGR/NR3C2/ESR1/AR/NR3C1/CAV1 | 6 |
| GO: 0001085 | RNA polymerase II transcription factor binding | ESR1/AR/PPARG/FOS/AHR/NFE2L2 | 6 |
| GO: 0030331 | Estrogen receptor binding | ESR1/PPARG/PCNA/PARP1 | 4 |
| GO: 0001221 | Transcription cofactor binding | ESR1/RELA/AHR/NFE2L2 | 4 |
| GO: 0042826 | Histone deacetylase binding | RELA/CCND1/MAPK8/HIF1A/PARP1 | 5 |
| GO: 0001091 | RNA polymerase II basal transcription factor binding | ESR1/AR/AHR | 3 |
| GO: 0001223 | Transcription coactivator binding | ESR1/RELA/AHR | 3 |
| GO: 0005178 | Integrin binding | EGFR/ICAM1/VCAM1/PRKCA/IGF2 | 5 |
| GO: 0035257 | Nuclear hormone receptor binding | ESR1/PPARG/PCNA/HIF1A/PARP1 | 5 |
| GO: 0051117 | ATPase binding | PGR/ESR1/AR/CAV1 | 4 |
| GO: 0033613 | Activating transcription factor binding | PPARG/RELA/FOS/NFE2L2 | 4 |
| GO: 0035258 | Steroid hormone receptor binding | ESR1/PPARG/PCNA/PARP1 | 4 |
| GO: 0016504 | Peptidase activator activity | APP/CAV1/CASP1 | 3 |
| GO: 0051427 | Hormone receptor binding | ESR1/PPARG/PCNA/HIF1A/PARP1 | 5 |
| GO: 0042562 | Hormone binding | ACHE/AR/EGFR/NR3C1 | 4 |