Table 3.
Target enrichment pathway of Compound-Xueshuantong Capsule in diabetic retinopathy treatment.
| ID | Description | Gene ID | Count |
|---|---|---|---|
| hsa04933 | AGE-RAGE signaling pathway in diabetic complications | RELA/VEGFA/CCND1/IL6/CASP3/ICAM1/BCL2/MAPK8/SELE/VCAM1/PRKCA/NOS3 | 12 |
| hsa05418 | Fluid shear stress and atherosclerosis | RELA/VEGFA/ICAM1/GSTP1/BCL2/FOS/MAPK8/SELE/VCAM1/GSTM1/CAV1/NOS3/NFE2L2 | 13 |
| hsa04210 | Apoptosis | RELA/CASP9/CASP3/CASP7/MCL1/BIRC5/BCL2/FOS/MAPK8/RAF1/PARP1/CTSD | 12 |
| hsa04668 | TNF signaling pathway | RELA/IL6/CASP3/CASP7/ICAM1/FOS/MAPK8/SELE/VCAM1/IRF1 | 10 |
| hsa05210 | Colorectal cancer | EGFR/CCND1/CASP9/CASP3/BIRC5/BCL2/FOS/MAPK8/RAF1 | 9 |
| hsa05161 | Hepatitis B | RELA/CASP9/IL6/CASP3/PCNA/BIRC5/BCL2/FOS/MAPK8/RAF1/PRKCA | 11 |
| hsa05215 | Prostate cancer | AR/RELA/EGFR/CCND1/CASP9/GSTP1/BCL2/PLAU/RAF1 | 9 |
| hsa05167 | Kaposi sarcoma-associated herpesvirus infection | RELA/VEGFA/CCND1/CASP9/IL6/CASP3/ICAM1/FOS/MAPK8/RAF1/HIF1A | 11 |
| hsa05133 | Pertussis | RELA/IL6/CASP3/CASP7/FOS/MAPK8/IRF1/CASP1 | 8 |
| hsa04215 | Apoptosis-multiple species | CASP9/CASP3/CASP7/BIRC5/BCL2/MAPK8 | 6 |
| hsa05205 | Proteoglycans in cancer | ESR1/EGFR/VEGFA/CCND1/CASP3/PLAU/RAF1/PRKCA/HIF1A/CAV1/IGF2 | 11 |
| hsa04917 | Prolactin signaling pathway | ESR1/RELA/CCND1/FOS/MAPK8/RAF1/IRF1 | 7 |
| hsa04066 | HIF-1 signaling pathway | RELA/EGFR/VEGFA/IL6/BCL2/PRKCA/HIF1A/NOS3 | 8 |
| hsa05212 | Pancreatic cancer | RELA/EGFR/VEGFA/CCND1/CASP9/MAPK8/RAF1 | 7 |
| hsa05163 | Human cytomegalovirus infection | RELA/EGFR/VEGFA/CCND1/CASP9/IL6/CASP3/RAF1/PRKCA/PTGER3 | 10 |
| hsa04926 | Relaxin signaling pathway | RELA/CASP9/IL6/CASP3/CASP7/CASP1 | 6 |
| hsa05134 | Legionellosis | RELA/CASP9/IL6/CASP3/NFKBIA/CASP7/CASP8/HSF1/CASP1 | 9 |
| hsa04370 | VEGF signaling pathway | VEGFA/CASP9/RAF1/PRKCA/NOS3/HSPB1 | 6 |
| hsa04151 | PI3K-Akt signaling pathway | RELA/EGFR/VEGFA/CCND1/CASP9/IL6/MCL1/BCL2/RAF1/PRKCA/NOS3/IGF2 | 12 |
| hsa04915 | Estrogen signaling pathway | PGR/ESR1/EGFR/BCL2/FOS/RAF1/NOS3/CTSD | 8 |