Table 2.
Liver haemodynamics | |
Free hepatic venous pressure (mm Hg) | 16 ± 4 (17 [14-19]) |
Wedged hepatic venous pressure (mm Hg) | 17 ± 5 (18 [14-20]) |
Hepatic venous pressure gradient (mm Hg) | 1.4 ± 0.3 (1 [0-2]) |
Liver biopsy | |
Sinusoidal dilation | 56 (100%) |
Sinusoidal fibrosis (categories 1-4) | 56 (100%) |
Portal fibrosis (categories 1-4) | 54 (94%) |
Liver disease severity | |
VAST (normal < 1) (n = 14) | 2.3 ± 1.0 |
APRI (normal < 0.3) | 0.5 ± 0.2 |
Child-Pugh score (normal < 5) | 6 ± 2 |
MELD score (normal < 6) | 13 ± 2 |
MELD-XI score (normal < 11) | 10 ± 2 |
Liver function | |
AST (U/L) (normal 8-43) | 39 (27-61) |
ALT (U/L) (normal 7-45) | 41 (29-76) |
ALP (U/L) (normal 37-104) | 92 (63-128) |
Total bilirubin (mg/dL) (normal 0.1-1.2) | 1.3 (0.8-1.8) |
Direct bilirubin (mg/dL) (normal 0-0.3) | 0.3 (0.1-0.6) |
Albumin (g/dL) (normal 3.5-5.0) | 3.9 (3.2-4.1) |
Alpha-fetoprotein (ng/mL) (normal < 0.6) | 3 (1-7) |
INR∗ (normal < 1.2) | 2.4 (1.8-2.9) |
INR† (normal < 1.2) | 1.3 (1.0-1.5) |
Platelet (×109/L) (normal 150-450) | 153 (122-264) |
Data are presented as mean ± standard deviation and median (interquartile range).
ALP, alkaline phosphatase; ALT, alanine aminotransferase; APRI, aspartate aminotransferase to platelet ratio index; AST, aspartate aminotransferase; INR international normalized ratio; MELD, model for end-stage liver disease; MELD-XI, model of end-stage liver disease excluding INR; VAST, varices, ascites, splenomegaly, and thrombocytopenia.
INR in all patients.
INR excluding patients receiving warfarin