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. 2020 Sep 17;10:15271. doi: 10.1038/s41598-020-72227-9

Figure 5.

Figure 5

Markers of central sensitization were not altered in the OA post-traumatic DMM model. The protein levels of c-Fos (A), p-ERK1/2 (B), GFAP (C) and IBA-1 (D) were quantified in the spinal cord of the DMM mice 12 weeks after surgery by western blot. The p-ERK1/2 expression was normalized to ERK1/2, and the c-Fos, GFAP and IBA-1 expression were normalized to the GAPDH. No differences were observed in the expression levels of both markers between DMM and sham-operated mice. Results are presented as mean ± SEM, n = 5 per group.