Table 2.
The association of disease onset sites with the APPs sCD14, LBP, and CRP.
| Arm (N = 44, 44.0%) | Leg (N = 28, 28.0%) | Bulbar (N = 25, 25.0%) | Other (N = 3, 3.0%) | p-value (Kruskal–Wallis test) | |
|---|---|---|---|---|---|
| sCD14 | |||||
| Median (range) | 3.2 (2.3, 4.2) | 2.9 (2.3, 4.2) | 3.3 (2.4, 4.4) | 3.1 (2.4, 3.1) | 0.078 |
| LBP | |||||
| Median (range) | 41.3 (21.7, 59.8) | 35.0 (20.2, 63.9) | 42.7 (15.7, 65.2) | 34.0 (31.3, 40.1) | 0.097 |
| CRP | |||||
| Median (range) | 4.9 (0.85, 9.6) | 3.8 (0.81, 11.0) | 5.2 (0.38, 10.3) | 4.1 (2.1, 4.2) | 0.195 |
| Age at first symp | |||||
| Median (range) | 54 (30.2, 80.9) | 61 (41.8, 77.0) | 66 (32.5, 79.3) | 61 (47.7, 63.3) | 0.019 |
| Age at DX | |||||
| Median (range) | 58 (32.2, 82.5) | 63 (42.9, 80.5) | 67 (33.1, 81.4) | 64 (52.1, 64.7) | 0.038 |
Patients with leg onset had lower APP levels. In contrast, patients with bulbar onset had higher APP levels. Patients with arm onset were younger than those with other sites of disease onset. There was no correlation between the patients’ ages at diagnoses and progression rates.
DX diagnosis.