Table 1.
Demographic and Clinical Characteristics at Time of First Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Polymerase Chain Reaction (PCR) Assay in Serum, by SARS-CoV-2 Serum PCR Status
| Demographics | PCR Negative (n = 106) |
PCR Positive (n = 61) |
Complete Data, No. (%) |
|---|---|---|---|
| Age, y | 53 (45–67) | 63 (52–74) | 167 (100) |
| Sex, No. (%), female:male | 36:70 (34:66) | 23:38 (38:62) | 167 (100) |
| Any comorbidity, No. (%) | 74 (70) | 48 (79) | 167 (100) |
| Pulmonary disease, No. (%) | 19 (18) | 10 (16) | 167 (100) |
| Any cardiovascular disease, No. (%) | 15 (14) | 18 (30) | 167 (100) |
| Hypertension, No. (%) | 35 (33) | 30 (49) | 167 (100) |
| Diabetes mellitus, No. (%) | 21 (20) | 13 (21) | 167 (100) |
| Liver disease, No. (%) | 3 (3) | 0 (0) | 167 (100) |
| Chronic renal disease, No. (%) | 4 (4) | 8 (13) | 167 (100) |
| Malignancy, No. (%) | 3 (3) | 1 (2) | 167 (100) |
| Immunosuppression, No. (%) | 1 (1) | 5 (8) | 167 (100) |
| Body mass index, kg/m2 | 29 (25–32) | 27 (25–31) | 157 (94) |
| Days after symptom onset for sampling | 10 (8–12) | 9 (8–11) | 165 (99) |
| Days after admission for sampling | 1 (1–2) | 1 (1–2) | 167 (100) |
| Peak temperature, °C | 38.1 (37.4–38.9) | 39 (38.4–39.5) | 167 (100) |
| Peak oxygen demand, L/min | 0 (0–2) | 3 (1–6) | 167 (100) |
| C-reactive protein, mg/L | 93 (49–168) | 115 (74–240) | 165 (99) |
| Procalcitonin, μg/L | 0.17 (0.1–0.4) | 0.32 (0.2–1.2) | 107 (64) |
| Neutrophil, × 109/L | 4.7 (3.4–6.6) | 5.6 (3.6–8.0) | 142 (85) |
| Lymphocyte, × 109/L | 1.1 (0.8–1.4) | 0.8 (0.6–1.3) | 142 (85) |
| Neutrophil/lymphocyte ratio | 4.6 (2.8–7.6) | 6.4 (4.1–10.9) | 142 (85) |
| Troponin T, ng/L | 8 (5–10) | 13 (8–24) | 110 (66) |
| D-dimer, mg/L | 0.8 (0.5–1.3) | 1.0 (0.7–1.8) | 105 (63) |
| Part of phase 1 or 2 convalescent plasma therapy study, No. (%) | 4 (4) | 28 (46) | 167 (100) |
| Corticosteroid treatment, No. (%) | 1 (1) | 3 (5) | 167 (100) |
Data are presented as median (interquartile range) unless otherwise indicated.
Abbreviation: PCR, polymerase chain reaction.