Key variates and efficacy outcomes of axicabtagene ciloleucel. (A) Overall response rate (ORR) stratified by multiple covariates. (B) Duration of response curves stratified by ZUMA-1 eligibility and use of bridging therapy. (C) Progression-free survival (PFS) stratified by ZUMA-1 eligibility and use of bridging therapy. (D) Overall survival (OS) stratified by ZUMA-1 eligibility and use of bridging therapy. CLL, chronic lymphocytic leukemia; CRS, cytokine release syndrome; DLBCL, diffuse large B cell lymphoma; ECOG, Eastern Cooperative Oncology Group; FL, follicular lymphoma; GCB, germinal center B cell; HGBL, high-grade B-cell lymphoma; MZL, marginal zone lymphoma; NR, not reached; NT, neurotoxicity; PMBCL, primary mediastinal large B-cell lymphoma; ZE, ZUMA-1 eligible; ZI, ZUMA-1 ineligible for reasons other than bridging therapy; ZI-BR, ZUMA-1 ineligible solely because of the use of bridging therapy.