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Frequency of neurological symptoms in children with SARS-CoV-2 infection
| Symptoms | Number of studies/case reports (number of participants) | Predominant type of cases included | Number of patients with symptoms | Pooled estimates % (95% CI) | Heterogeneity (I2%) | p-Value for I2 |
|---|---|---|---|---|---|---|
| Fatigue/myalgia | 11 (3129) | Mild | 449 | 14.3 (13.1–15.6) | 35 | 0.006 |
| Headache | 8 (3036) | Mild | 114 | 3.7 (3.1–4.4) | 31 | 0.01 |
| Seizure | 7 (380) | Severe | 12 | 3.1 (1.8–5.4) | 27 | 0.02 |
| Encephalopathy | 5 (198) | Severe | 25 | 12.6 (8.7–17.9) | 59 | 0.001 |
