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. 2020 Sep 15;153(11):115101. doi: 10.1063/5.0020458

FIG. 3.

FIG. 3.

Flexibility of the catalytic triad regions of the PLpros. (a) Root-mean-square fluctuations of the Cα atoms of the catalytic triad and nearby five residues in SARS-CoV-2, SARS-CoV, and MERS-CoV PLpros. The sequences of SARS-CoV-2/CoV and MERS-CoV PLpros are aligned, and the residue numbering of SARS-CoV-2 PLpro is used. (b) A snapshot of the catalytic triad regions in SARS-CoV-2 PLpro. Cys111 (yellow), His272 (blue), and Asp286 (red) side chains are explicitly shown, and the nearby residues are colored green.