Table 6.
The potential correlation of ANO8 mutations with clinical and laboratory data in samples from 151 Han Chinese patients with ICP disease
| Featuresa | ICP without ANO8 mutations | ICP with ANO8 mutations | P value |
|---|---|---|---|
| Basic information | |||
| Age (years, mean ± SD, Nb) | 29.43 ± 5.31 (n = 143) | 28.5 ± 3.43 (n = 08) | 0.62 |
| BMI (kg/m2) | 25.82 ± 3.37 (n = 129) | 25.36 ± 3.62 (n = 08) | 0.71 |
| Laboratory, mean (range, N) | |||
| K (mmol/L) | 4.00 (3.20–4.90, 134) | 3.94 (3.6–4.3, 7) | 0.61 |
| Na (mmol/L) | 137.47 (132.00–143.00, 133) | 136.71 (134.00–139.00, 7) | 0.41 |
| CL (mmol/L) | 104.17 (97.00–112.00, 133) | 102.71 (100.00–104.00, 7) | 0.17 |
| Ca (mmol/L) | 2.31 (2.00–2.90, 133) | 2.33 (2.23–2.48, 7) | 0.71 |
| Mg (mmol/L) | 0.81 (0.60–1.89, 133) | 0.79 (0.70–0.87, 7) | 0.36 |
| P (mmol/L) | 1.12 (0.72–1.60, 133) | 1.04 (0.70–1.30, 7) | 0.21 |
| WBC (× 109) | 8.61 (4.37–24.23, 142) | 7.75 (5.90–10.03, 8) | 0.40 |
| RBC (× 1012) | 3.85 (2.96–4.98, 142) | 3.59 (3.25–4.02, 8) | 0.08 |
| PLT (× 109) | 197.61 (75.00–412.00, 142) | 212.25 (112.00–328.00, 8) | 0.52 |
| RDW-SD (fL) | 45.93 (36.20–67.30, 142) | 44.30 (39.70–49.30, 8) | 0.34 |
| TBA (µmol/L) | 40.81 (4.20–286.80, 143) | 93.36 (14.80–185.50, 8) | 0.038 |
| CHOL (mmol/L) | 6.41 (3.35–10.95, 137) | 6.40 (4.91–8.75, 7) | 0.98 |
| TG (mmol/L) | 3.59 (1.20–10.44, 137) | 3.88 (1.56–11.10, 7) | 0.82 |
| Birth weight (kg) | 3.06 (1.23–5.30, 112) | 2.86 (2.45–3.35, 5) | 0.36 |
| Bleeding amount (ml) | 251.74 (90.00 − 810.00, 109) | 310.00 (190.00–600.00, 5) | 0.48 |
aSee the footnotes in Table 1
bN: total number