Skip to main content
. 2020 Sep 18;21:239. doi: 10.1186/s12931-020-01498-7

Table 3.

Compilation of the cell-specific immunohistochemical results and demographic associations

Factor Airway cell phenotype Demographic association
MUC1 Basal cell

↑ Smokers and Chronic bronchitis

Correlated negatively with lung functions in male Smokers

Correlated positively with pack-years

MUC4 Goblet cells ↑ Smokers
EGFR1 Basal cells No change
EGFR2 Basal and ciliated cells

↑ Healthy

Correlated positively with lung functions

Correlated negatively with pack-years and current cigarette consumption

Alterations in abundance are expressed in comparison to the healthy Never-smoker group