Table 1.
Baseline characteristics
| Parameter | Training (n = 144) | Validation (n = 150) | P value |
|---|---|---|---|
| Sex | .88 | ||
| No. of men | 117 (81.3) | 120 (80.0) | |
| No. of women | 27 (18.7) | 30 (20.0) | |
| Age | .49 | ||
| < 60 (years) | 68 (47.2) | 77 (51.3) | |
| ≥ 60 (years) | 76 (52.8) | 73 (48.7) | |
| CT-reported cirrhosis | .81 | ||
| Cirrhosis-negative | 98 (68.1) | 100 (66.7) | |
| Cirrhosis-positive | 46 (31.9) | 50 (33.3) | |
| Laboratory findingsa | |||
| AST (IU/mL) | 31.6 (23.5–48.2) | 29.3 (21.1–38.5) | .13 |
| ALT (IU/mL) | 31.2 (22.0–50.0) | 26.9 (19.6–39.6) | .07 |
| GGT (IU/mL) | 53.5 (32.0–111.4) | 54.9 (29.5–91.2) | .26 |
| Total bilirubin (ng/mL) | 13.5 (9.2–18.5) | 12.9 (10.0–17.8) | .16 |
| Platelet count (109/L) | 141.5 (91.8–182.3) | 138.5 (100.5–188.3) | .70 |
| INR | 1.04 (0.98–1.11) | 1.04 (0.98–1.11) | .31 |
| APRI | 0.63 (0.41–0.98) | 0.53 (0.33–0.91) | .16 |
| FIB-4 | 2.65 (1.70–4.14) | 2.30 (1.62–3.76) | .21 |
| Histologic grade | .59 | ||
| F0 | 18 (12.5) | 14 (9.3) | .46 |
| F1 | 24 (16.7) | 32 (21.3) | .37 |
| F2 | 13 (9.0) | 18 (12.0) | .45 |
| F3 | 26 (18.1) | 29 (19.3) | .88 |
| F4 | 63 (43.8) | 57 (38.0) | .34 |
Note. —Except where indicated, data are numbers of patients, with percentages in parentheses. ALT alanine aminotransferase, APRI aspartate aminotransferase-to-platelet ratio, AST aspartate aminotransferase, FIB-4 fibrosis-4 index, GGT γ-glutamyl transferase, INR international normalized ratio
aData are medians, with interquartile range in parentheses